研究员(Professor)

Photo: 
Name: 
Professor Yi XIN
Professor
Email: 
xinyi@hainanu.edu.cn

姓名(Name: 辛一 Yi Xin

Email: xinyi@hainanu.edu.cn

个人简介

博士,研究员,博士生导师,主要研究真核微藻油脂代谢和代谢工程,以及油脂代谢酶类的高通量筛选。目前已在SCI知名期刊发表学术论文十余篇,其中真核微藻油脂理性设计作为重要科研进展,录入“2019年中国工业生物技术白皮书。担任Scientific ReportAlgal ResearchEnvironmental Science & Technology等学术期刊审稿人。主持微藻合成生物学国家重点研发子任务、国家军工项目、国家青年基金、山东省青年基金等共计700余万元。申请国家发明专利9项。

Research Interests

Prof. Xin has developed a series of stable and high-efficient engineering tools (such as overexpression, RNAi, CRIPSR/Cas9, etc.) in an industrial microalga, Nannochloropsis oceanica. By these innovative research tools, Prof. Xin has delineated and designed lipid metabolic processes in N. oceanica. Selected experience includes: (1) Microalgal genetic engineering on lipid metabolism (Zhang et al 2022 Nat Commun; Xin et al 2019 Mol Plant; Xin et al 2017 Mol Plant); (2) Development of tools on microalgal genetic engineering (Wang et al 2020 Sci Adv; Wei et al 2017 Plant J; Wang et al 2016 Plant J).

 

学习工作经历

2022.06-至今 海南大学 南海海洋资源利用国家重点实验室 研究员

2020.08-2022.05中国科学院青岛生物能源与过程研究所 单细胞中心 工具酶研究组 组长

2020.01-2022.05中国科学院青岛生物能源与过程研究所 副研究员

2017.08-2019.12 中国科学院青岛生物能源与过程研究所 助理研究员

2015.02-2017.07中国科学院青岛生物能源与过程研究所 博士后

2010.09-2015.01中国科学院青岛生物能源与过程研究所 生化与分子生物学 博士 (导师:徐健 研究员)

2007.09-2010.06中国科学院海洋研究所 海洋生物学 硕士(导师:刘晓 研究员)

2003.09-2007.06 中国海洋大学 生物技术 学士

 

Education & Research Experiences

2022.06-

Professor, State Key Laboratory of Marine Resources Utilization in South China Sea, Hainan University

2020.08-2022.05

Lead of Tool Enzyme Team, Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences (CAS)

2020.01-2022.05

Associated Professor, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences (CAS)

2017.08-2019.12

Assistant Professor, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences (CAS)

2015.02-2017.07

Postdoctor, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences (CAS)

2010.09-2015.01

Doctor, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences (CAS)

2007.09-2010.06

Doctor, Biochemistry and molecular biology, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences (CAS)

2007.09-2010.06

Mastor, Marine biology, Institute of Oceanology of the Chinese Academy of Sciences

2007.09-2010.06

Bachelor, Biotechnology, Ocean University of China

 

代表性论文(Featured Publications

1. Xin Y#, Shen C#, She YT, Chen H, Wei L, Yoon KS, Han DX, Hu Q, Xu J*. Biosynthesis of triacylglycerol molecules with tailored PUFA profile in industrial microalgae. Molecular Plant. 2019, 12: 474.

2. Xin Y#, Lu YD#, Lee YY#, Wei L, Jia J, Wang QT, Wang DM, Bai FL, Hu HH, Hu Q, Liu J*, Li YT*, Xu J*. Producing designer oils in industrial microalgae by rational modulation of co-evolving type-2 diacylglycerol acyltransferases. Molecular Plant. 2017, 10: 1523.

3. Zhang P#, Xin Y#, He YH#, Tang XF, Shen C, Wang QT, Lv NN, Li Y, Hu Q, Xu J*.  Exploring a blue-light-sensing transcriptional factor to double the peak productivity of oil in Nannochloropsis oceanica. Nature Communications. 2022, 13: 1664.

4. Wang XX#, Xin Y#, Ren LH#, Sun Z, Zhu PF, Ji YT, Li CY, Xu J*, Ma B*. Positive dielectrophoresis based Raman-activated droplet sorting for culture-free and label-free screening of enzyme function in vivo. Science Advances. 2020, 6: eabb3521.

5. Wei L#, Xin Y#, Wang QT, Yang J, Hu HH*, Xu J*. RNAi-based targeted gene-knockdown in the model oleaginous microalgae Nannochloropsis oceanica. Plant Journal. 2017, 89: 1236.

6. Xin Y#, Yang M#, Yin H*, Yang JM*. Improvement of Ethanol Tolerance by Inactive Protoplast Fusion in Saccharomyces cerevisiae. Biomed Research International. 2020, 1979318.

7. Wei L#, Xin Y#, Wang DM, Jing XY, Zhou Q, Su XQ, Jia J, Ning K, Chen F, Hu Q, Xu J*. Nannochloropsis plastid and mitochondrial phylogenomes reveal organelle diversification mechanism and intragenus phylotyping strategy in microalgae. BMC Genomics, 2013, 14: 534.

8. Xin Y, Ren JF, Liu X*. Mitogenome of the small abalone Haliotis diversicolor Reeve and phylogenetic analysis within Gastropoda. Marine Genomics, 2011, 4: 253.